Is Belviq Lorcaserin 10 mg effective?

Lorcaserin has completed phase III clinic trials and while results have not been as promising as those for Qsiva, it does seem to have a good safety profile. Two separate phase III clinic trials (BLOOM and BLOSSOM) evaluated almost 7,200 patients in total over a 2-year period. After 1 year of treatment about two thirds of patients had lost at least 5% of their body weight. The average weight loss was between 17 and 18 pounds and patients saw their blood pressure and heart rate go down.

In the BLOOM trial, 3,182 patients took part, with either a BMI of over 30 or a BMI of between 27 and 30 with another health condition such as Type 2 Diabetes, high blood pressure or high cholesterol. They were given 10mg of Lorcaserin daily or twice daily over two years. Data showed that after one year those completing the trial and taking the now licensed dose of two pills a day had the following results:

• 62.3% of patients lost at least 5% of their body weight, compared with 32.1% for those on the placebo
• 33.5% lost at least 10% of their body weight compared, with 13.8% for those taking the placebo

Some patients are high responders and it clearly does not work well for everyone. Anyone who has not lost 5% of the bodyweight by week 12 should discontinue.

Is Lorqess (Lorcaserin) safe?

Clinical trials are designed not only to determine if a medication works but also to make sure that it is safe for the general public to take.

In trials, Lorcaserin was well tolerated by the patients who took part in the trial and few adverse events were reported when compared with the placebo group. Most side effects were reported in the first year of the two-year trials. Transient headaches were the most common side effects, with 18% of patients experiencing them, compared with 11% in the placebo group. There were also reports of upper respiratory tract infections (14.8% vs. 11.9%.) and nausea (7.5% vs. 5.4%.) These side effects appeared to be the only ones with statistical significance.

No more patients reported feelings of depression, anxiety or suicidal thoughts than in the placebo group (in both groups, reports were infrequent) and the drug has good cardiovascular safety. Buy Belviq online

BELVIQ Side Effects and Risks

According to the FDA, common side effects of BELVIQ include headaches, dizziness, fatigue, nausea, dry mouth, and constipation. In diabetic patients, side effects are low blood sugar (hypoglycemia), headache, back pain, cough, and fatigue.The National Institutes of Health provides a full list of side effects that you should evaluate and discuss with your doctor before you take the medication.3 The drug is also not approved for patients who have experienced reactions to lorcaserin or any of the past product components

In the early stages of testing, researchers were concerned about cardiac issues in patients taking BELVIQ. But the FDA has since concluded that the drug is unlikely to cause the heart valve problems that were at issue in the early studies. However, BELVIQ has not been studied in patients with serious valvular heart disease, and the FDA recommends that patients with congestive heart failure be especially cautious when taking the medication.

In addition, according to the New England Journal of Medicine, there are some concerns that the drug may carry a risk of psychiatric or psychological problems, especially for people who are taking certain medications.

In February 2020, the FDA requested the withdrawal of BELVIQ from the market due to the increased occurrence of cancer. A double-blind, placebo controlled trial was conducted over 5 years in 12,000. The results revealed many types of cancers occurring more frequently in the group taking the real drug. These cancers include pancreatic, colorectal, and lung.6 The FDA believes that the risks of taking this drug outweigh the benefits.

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